Ihilov clinics invest heavily in medical equipment and technology, modern linear accelerators, and the latest laboratory methods for molecular and genetic testing. Many doctors at the medical center are recognized world experts in the treatment of malignant lymphomatous polyposis in Israel and worldwide. They teach at leading medical universities, initiate, and conduct research programs.
Each patient at Ihilov is provided with an individualized treatment plan based on the latest scientific data and unique characteristics of the disease. Patient cases are jointly reviewed by specialists from various fields – oncologists, hematologists, radiologists, and surgeons, allowing for the analysis and consideration of all therapy options.
The clinics provide comprehensive and thorough support to patients and their families, including psychological assistance, help with travel arrangements, and accommodation in the country.
Israeli clinics have extensive experience in serving international patients, providing translator and coordinator services.
About the disease
Malignant lymphomatous polyposis belongs to the non-follicular lymphomas of mantle cell origin. It is a rare subtype of non-Hodgkin lymphoma characterized by the presence of malignant B-lymphocytes – cells originating from the mantle zone of lymph nodes.
The specific causes of mantle cell lymphoma are not established. It is believed that a mutation in the cyclin D1 gene (CCND1), which regulates the cell cycle, plays a key role in the development of the disease.
Signs of malignant lymphomatous polyposis include:
- enlarged lymph nodes, often painless;
- splenomegaly – enlargement of the spleen;
- fever, night sweats, and weight loss without clear reason;
- fatigue, general weakness, tiredness;
- gastrointestinal symptoms.
Treatment methods for the disease
Treatment of mantle cell lymphoma depends on the stage of the disease, the overall health of the patient, their age, and personal characteristics of the disease. The multidisciplinary team at Ihilov evaluates all aspects of treatment, goals, prognosis, possible side effects, and risks of each method.
Chemotherapy
This is the standard method for treating malignant lymphomatous polyposis. Therapy is based on sequential sessions of administering drugs capable of destroying cancer cells. Treatment is conducted according to individualized schemes, which may include different doses and combinations of systemic antitumor drugs. Mandatory breaks for recovery are taken between therapy sessions.
Immunotherapy
The feature of immunotherapeutic agents is the ability to specifically target and destroy cancer cells. Targeted sites are determined by characteristic antigens using molecular-genetic expertise. Immunotherapy is often used in combination with chemotherapy to enhance overall effectiveness, helping to boost the immune response against malignant cells.
Targeted therapy
Another innovative type of treatment. Targeted therapy drugs “track” and destroy specific biomolecules involved in the growth and survival processes of cancer cells. Compared to standard chemotherapy, the advantages of these laboratory-synthesized substances are that they are more selective – acting narrowly and selectively and have fewer side effects.
Radiotherapy
The use of localized radiation is recommended for:
- controlling localized forms of malignant lymphomatous polyposis;
- alleviating symptoms.
The Ihilov clinic is equipped with the latest TrueBeam and Lunac linear accelerators. This modern equipment allows for very precise targeting of tumours while minimizing impact on surrounding healthy tissues. Their advantages include the highest precision and controllability of the radiation dose, the ability to modulate beam intensity (IMRT), as well as real-time monitoring and visualization of tumour formations (IGRT).
Stem cell transplantation
For some patients with malignant lymphomatous polyposis, high-dose chemotherapy followed by allogeneic or autologous stem cell transplantation may be recommended. This approach involves transplanting the patient's own stem cells or those taken from a healthy donor to restore and stimulate the production of healthy stem cells.
- Stem cell treatment
- Radiotherapy
- Chemotherapy
Diagnostic methods for the disease
At the Ihilov clinic, the diagnosis of malignant lymphomatous polyposis is carried out in several stages and takes three working days.
First day
The doctor conducts a detailed medical history, assessing the symptoms and medical history of the patient. A physical examination is performed to check for enlarged lymph nodes, splenomegaly, and other physical signs that may be associated with the disease.
Second day
- Laboratory blood tests
- Biopsy and histological analysis
- Molecular-genetic tests
- Imaging studies
- Consultations with narrow specialists
Third day
Based on the obtained diagnostic information and assessment of the patient's overall health, age, and comorbidities, the multidisciplinary team of doctors develops a treatment plan. A thorough and stepwise diagnosis allows for the accurate determination of the presence and stage of malignant lymphomatous polyposis and the selection of the optimal treatment scheme for each specific case.
- Biopsy and histological studies
How much does treatment cost
Israel is considered one of the countries with the best availability of new and experimental drugs, diagnostic methods, and therapies. The cost of the treatment program at the Ihilov clinic depends on the patient's condition – this affects the volume and complexity of diagnostic procedures, the need for consultations with specialists from related disciplines, the composition of the treatment program, and the price of medications.
Call the phone number listed on the website to find out how much a stay at the clinic costs. Get detailed consultation on how to organize treatment in Israel, ratings, reviews, and transfers. You can ask any questions in the online chat or write in the special feedback form.
Advantages of treating malignant lymphomatous polyposis in Israel
- Use of advanced technologies
- Highly qualified specialists
- Individual approach
- Interdisciplinary consultations
- Support and experience working with international patients
The Ihilov clinic regularly updates and expands its diagnostic and therapeutic methods to meet the latest global standards. You can schedule a video call via Zoom or Skype and receive detailed consultation on new treatment methods for malignant lymphomatous polyposis and the capabilities of the medical center regarding your case.