Professor Naftali SternEndocrinologist
For patients diagnosed with "trabecular adenoma," there is a wide range of modern treatment methods, and it is important to note that at the Ichilov clinic, individual and maximally effective approaches are tailored for each case. When it comes to seeking advanced medical solutions, Israel should be considered the optimal choice.
Here, special attention is paid to the ultramodern approaches, as each therapeutic solution is based on the latest achievements in global medicine and innovative technologies, significantly increasing the chances of successful recovery. No less important is the collegial review of the case, as each medical case is thoroughly analyzed by a team of highly qualified specialists from various fields, ensuring the most accurate diagnosis and the development of a comprehensive treatment plan. In addition to the highest level of medical care, the Ichilov clinic offers excellent accommodation conditions for patients, creating a comfortable and supportive atmosphere that is essential during treatment and recovery.
About the Disease
Trabecular adenoma is a benign neoplasm of the thyroid gland, the uniqueness of which lies in the special structure of the cells that form long strands or trabeculae, resembling the structure of the gland during intrauterine development. This definition emphasizes its specific histological pattern, distinguishing it from other types of adenomas and requiring special attention during diagnosis.
The causes of trabecular adenoma are not fully understood, but it is believed that its development may be associated with a number of factors such as genetic predisposition, hormonal imbalances, iodine deficiency in the body, and exposure to adverse environmental conditions. These factors can provoke abnormal growth of thyroid cells, leading to the formation of this tumour.
Although trabecular adenoma is benign, its presence can cause certain discomfort, manifesting as a sensation of a foreign body or pressure in the neck area, difficulty swallowing (dysphagia), or even breathing (dyspnea), especially with significant tumour enlargement. Additionally, in rare cases, despite its benign nature, symptoms related to the hormonal activity of the tumour may manifest, which can also affect the overall well-being of the patient.
Treatment Methods for Trabecular Adenoma
The choice of treatment methods for trabecular adenoma is determined by the size of the tumour, its localization, the stage of the disease, and the overall condition of the patient. If necessary, specialists apply a combined approach, combining several treatment methods to achieve maximum effectiveness.
Surgical Treatment
Surgical intervention is used for localized forms of trabecular adenoma as the primary method of radical treatment. Modern surgical technologies include laparoscopic and robotic systems that allow for precision operations through minimal incisions. Intraoperative navigation and ultrasound control ensure the precise removal of the tumour while preserving healthy tissues, achieving complete remission in most cases.
Radiotherapy
Radiation therapy is prescribed in inoperable cases or as adjuvant treatment after surgical intervention. Technologies such as stereotactic radiosurgery, intensity-modulated radiation therapy, and proton therapy are used. Modern linear accelerators with visual control systems allow for the delivery of high doses of radiation directly to the tumour tissue, minimizing the impact on surrounding structures and ensuring long-term remission.
Chemotherapy
Systemic chemotherapy is used for advanced forms of the disease or high risk of metastasis. Modern regimens include targeted drugs, monoclonal antibodies, and angiogenesis inhibitors. Personalized selection of chemotherapeutic agents is based on the molecular-genetic profile of the tumour, allowing for maximum treatment effectiveness and prolonging the remission period in patients with metastatic forms of the disease.
Radiofrequency Ablation
This minimally invasive method is used for small tumour sizes or in cases where surgical treatment is contraindicated. The technology uses high-frequency electromagnetic waves delivered through thin electrodes under CT or MRI navigation. The procedure causes thermal destruction of tumour cells at temperatures of 50-100°C, ensuring local remission with minimal damage to surrounding tissues and quick recovery.
Cryoablation
The cryodestruction method is used for treating localized small tumours as an alternative to surgical intervention. The technology is based on cyclic freezing and thawing of the tumour tissue using cryoprobes under ultrasound or MRI control. The temperature in the affected area reaches -40°C, leading to the formation of intracellular ice crystals and necrosis of tumour cells, ensuring sustained remission of the disease.
Endoscopic Treatment
Endoscopic methods are used for localized thyroid adenomas for minimally invasive tumour removal. The technology includes the use of endoscopes with HD cameras, micro-instruments, and electrocautery through small incisions. Robot-assisted endoscopic systems provide three-dimensional visualization and precision movements, allowing for complete tumour removal while preserving gland function and achieving long-term remission.
Sclerotherapy
This interventional treatment method is used for cystic forms of trabecular adenoma or in cases where surgical intervention is contraindicated. The technology is based on puncture introduction of sclerosing agents under ultrasound control. Ethanol or other sclerosing agents cause devascularization and fibrosis of the tumour tissue, leading to significant reduction in the size of the formation and achieving sustained remission without surgical intervention.
Hormonal Therapy
Conservative treatment is prescribed for functionally active adenomas to correct hormonal imbalance before surgical treatment or as standalone therapy. Antithyroid medications, beta-blockers, and somatostatin analogs are used depending on the type of hormonal activity. Medication therapy normalizes thyroid hormone levels and allows for clinical remission of endocrine disorders in most patients with functioning adenomas.
- Hormonal Therapy
- Radiotherapy
- Chemotherapy
- Laparoscopy
- Cryoablation
- Robotic Surgery
Diagnostic Methods for the Disease
All diagnostic procedures for treating trabecular adenoma at the Ichilov clinic are planned in advance and usually take about three days. This approach allows for an accurate and comprehensive picture of the disease to be obtained in the shortest possible time and to begin treatment without delay.
First Day
Upon arrival at the clinic, the patient undergoes a consultation with the attending physician. The specialist conducts a thorough examination, asks detailed questions about symptoms and medical history, and determines the list of necessary diagnostic procedures that will help assess the patient's condition comprehensively and accurately.
Second Day
On the second day, a series of laboratory and instrumental studies are performed to clarify the diagnosis and determine the treatment strategy:
- complete blood count
- biochemical blood test
- thyroid hormone test
- calcitonin test
- urinalysis
- ultrasound of the thyroid gland
- fine-needle aspiration biopsy
- scintigraphy
- CT of the neck
- MRI of the soft tissues of the neck
- PET-CT
- ECG
- chest X-ray
Third Day
After completing all the studies, the team of specialists begins discussing the obtained data. The multidisciplinary group includes an endocrinologist, oncologist, surgeon, radiologist, and, if necessary, other specialized doctors. The collaborative work of experts allows for the creation of a personalized therapeutic plan that takes into account all aspects of the patient's condition. This approach ensures more accurate and effective treatment, reduces risks, and increases the chances of a favorable outcome.
- Thyroid Biopsy in Israel
- Computed Tomography
- Magnetic Resonance Imaging (MRI)
- Diagnosis — PET CT
- X-ray
- Ultrasound
- Blood Biochemistry
How Much Does Treatment Cost in Israel
The cost of treatment is formed individually and depends on the volume of necessary diagnostic procedures, the chosen method of therapy, the qualifications of specialists, and the duration of hospitalization. The exact price is calculated only after the preliminary examination and treatment plan is established.
To find out the cost of treatment in your case, contact the consultant by phone listed on the website. The specialist will provide an estimated budget, discuss possible treatment options, the organization of the trip, and help prepare medical documents for preliminary review.
Advantages of Treatment in Israel
- Highly qualified specialists with extensive experience.
- Advanced technologies and innovative treatment methods.
- Individual approach to each patient.
- Comprehensive examination and accurate diagnosis.
- Comfortable conditions for staying in the clinic.
Even before arriving at the Israeli clinic, you can order an online consultation with the necessary specialist to receive recommendations, answers to all your questions, and gain confidence in the chosen treatment plan.