The foundation of our musculoskeletal system is bone tissue. Like other tissues in our body, it can be destroyed and restored, and metabolic processes also occur within it. Our bones need phosphorus and calcium, and the processes of destruction and construction of bone tissue are regulated by hormones. If the balance between these processes or in phosphorus-calcium metabolism is disrupted, it is referred to as bone metabolism disorders.
Causes
Bone metabolism disorders manifest as a range of diseases. Osteoporosis is a disruption of the balance between destructive and restorative processes. This condition is characteristic of elderly individuals. Excessive secretion of parathyroid hormone by the parathyroid gland leads to a condition called hyperparathyroidism. There are congenital diseases of bone tissue. Their occurrence is associated with genetic defects or maternal diseases during intrauterine development. In cases of calcium metabolism disorders or insufficient calcium intake, hypocalcemia may develop – a decrease in calcium levels in the blood.
Symptoms of Bone Metabolism Disorders
The symptoms of bone metabolism disorders depend on the type of disease. For example, in osteoporosis, increased bone fragility is observed, leading to frequent fractures even with minor loads. Due to disruptions in calcium-phosphorus metabolic processes (hyperparathyroidism), bones become extremely brittle.
Diagnosis of Bone Metabolism Disorders in Israel
The primary diagnostic method in Israel for identifying patients with bone metabolic disorders is the determination of biochemical markers of bone resorption and remodeling. This method also allows for the assessment of the effectiveness of the prescribed treatment course.
Treatment of Bone Metabolism Disorders in Israel
Treatment of this pathology in Israel depends on its severity and symptoms. Bisphosphonates, calcitonin, fluorides, and medications that improve vitamin D metabolism are prescribed. In cases of severe pain syndrome, calcitonin may be used in conjunction with calcium salts and vitamin D. Treatment of bone metabolism disorders is prolonged, so periodic monitoring of bone density is necessary to check the effectiveness of the treatment course. The foundation of our musculoskeletal system is bone tissue. Like other tissues in our body, it can be destroyed and restored, and metabolic processes also occur within it. Our bones need phosphorus and calcium, and the processes of destruction and construction of bone tissue are regulated by hormones. If the balance between these processes or in phosphorus-calcium metabolism is disrupted, it is referred to as bone metabolism disorders.