The "Brain Tumors" subcluster brings together materials on the diagnosis and treatment of primary and metastatic tumors of the central nervous system at the Ichilov (Sourasky) Medical Center in Tel Aviv. Here you will find articles on specific histological types — from low-grade gliomas and glioblastomas to meningiomas, schwannomas, ependymomas, medulloblastomas, pituitary adenomas, and brain metastases in adults and children.
The neuro-oncology program at Ichilov is built around a multidisciplinary Tumor Board that includes a neurosurgeon, medical oncologist, radiation therapist, neuroradiologist, and neuropathologist. The strategy is tailored after a detailed MRI with tractography and spectroscopy, PET-CT, and molecular-genetic analysis of tumor tissue, including markers IDH1/2, MGMT, and 1p/19q. This approach allows for the separation of operable cases from candidates for radiosurgery and accurately plans the extent of intervention.
The surgical arsenal of the Sourasky clinic includes microsurgical craniotomy, including "awake craniotomy" — a procedure with the patient awake to preserve speech and motor areas, intraoperative MRI and neuronavigation, fluorescent visualization with 5-ALA, and transsphenoidal access to skull base tumors. For inoperable or residual lesions, stereotactic radiosurgery, CyberKnife, and next-generation linear accelerators are used, while systemic therapy is complemented by targeted drugs, immunotherapy, and participation in clinical trials.
Special attention is given to postoperative neuro-oncological rehabilitation: working with a speech therapist, neuropsychologist, and physiotherapist helps restore cognitive functions, speech, and motor skills. The hub contains both overview materials on nosologies and notes on breakthrough technologies used at Ichilov. Below are articles on the topic, diagnostic and treatment programs, as well as specialized neurosurgeons and oncologists who can be contacted directly.