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Ichilov Medical Center
Oncology

Treatment of Squamous Cell Carcinoma of the Esophagus in Israel — Innovative Methods and a Comprehensive Approach

According to recent studies, esophageal cancer ranks among the top ten most commonly diagnosed malignant diseases, with squamous cell carcinoma being the most frequently diagnosed type. Treatment of squamous cell carcinoma of the esophagus in Israel is conducted according to an individualized comprehensive program that includes the most effective modern methods. With timely initiation of therapy, more than 85% of patients achieve prolonged stable remission. In advanced stages of the disease, palliative therapy is provided to alleviate painful symptoms and normalize the patient's condition, allowing them to return to their usual life.

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In 20% of patients, esophageal oncopathology is diagnosed at an advanced stage, which is explained by the asymptomatic progression of the initial stages. Israeli clinics are equipped with the latest technology that allows for the detection of tumors of the smallest size, accurately determining their characteristics necessary for selecting the most effective drugs that do not harm the patient's body. Accurate diagnostics are also important for confirming the existing diagnosis, which is found to be incorrect in a quarter of patients from the former CIS countries. Additionally, the cost of treatment in Israel is accessible for medical tourists and significantly lower than in clinics in Western European countries and the USA.

Current Treatment Methods for the Disease

The choice of treatment methods depends on the stage of the pathology, the size and location of the tumor, the extent of the malignant process, and the overall condition of the patient. The individualized comprehensive program is based on the main methods of anti-tumor therapy: surgical removal of the neoplasm, radiotherapy, and chemotherapy.

Surgical Treatment

Depending on the size and stage of the tumor, various types of surgical interventions are used. In the early stages of the disease, when there are no metastases in the regional lymph nodes and distant organs, esophagectomy is most commonly performed — the removal of the segment of the esophagus involved in the malignant process, followed by the connection of the remaining part to the stomach. A localized tumor on the wall of the esophagus that has not spread to the deeper layers of tissue can be removed during esophagoscopy. In this case, a catheter with a conductor that delivers high-frequency electric current is introduced through the patient's larynx. The application of current to the tumor raises the temperature, resulting in the destruction of cancer cells.

Israeli surgeons prefer minimally invasive laparoscopic and endoscopic surgical methods. Surgical instruments and a laparoscope with a camera are introduced through several small incisions. Such operations are not associated with a high risk of bleeding and complications and are characterized by a short and uncomplicated recovery period. The patient's condition is continuously monitored in the first days after the procedure, and any painful symptoms are alleviated with medication.

Stenting

In the terminal stages of the oncological disease, patients typically present with conditions that make surgical intervention impossible. In such cases, a stent is placed to prevent narrowing of the esophagus and alleviate the patient's condition. The procedure is performed under ultrasound control. In cases of stenosis, electrocautery may also be prescribed to eliminate the narrowing of the esophagus and stop bleeding.

Photodynamic Therapy

This method is based on the introduction of a photosensitizing drug into the esophagus, which accumulates in pathological cells and significantly increases their sensitivity to light. Then, a laser is directed to the tumor endoscopically, and targeted irradiation of the malignant focus is performed. Under the influence of laser irradiation, the temperature increases, and cancer cells are literally vaporized. The destruction of malignant tissues leads to a reduction in tumor size and a favorable prognosis.

Radiotherapy

The effect of ionizing radiation has a destructive effect on cancer cells. To enhance effectiveness, radiotherapy is combined with chemotherapy. Radiotherapy is prescribed before surgical intervention to reduce the size of the tumor and facilitate its subsequent removal. After surgery, irradiation is aimed at destroying any remaining malignant cells in the patient's body and preventing recurrence.

In Israeli clinics, external beam radiation is performed on modern equipment using the latest techniques, such as IMRT (Intensity-Modulated Radiation Therapy). This method allows for the modulation of radiation intensity across different areas of the tumor while minimizing impact on healthy tissues. Another effective method is contact radiotherapy — brachytherapy, where a capsule containing a radioactive element is introduced directly into the tumor tissues. Internal irradiation of the tumor is highly effective and safe for the patient.

Chemotherapy

Chemotherapy can be used both in combination with radiotherapy and as a standalone treatment method. It is prescribed before and after surgical intervention to reduce tumor size, destroy remaining malignant cells, and prevent metastasis and recurrence. Numerous patient reviews indicate that Israeli clinics use the latest generation of chemotherapy drugs, which are much less toxic than traditional ones and cause fewer side effects.

Targeted Therapy

This innovative method is based on the targeted action of drugs specifically on cancer cells without damaging healthy ones. Studies show that the inclusion of targeted drugs in the treatment program increases its effectiveness by an average of 50%.

Immunotherapy

For the treatment of esophageal oncological diseases, immunotherapeutic agents based on monoclonal antibodies specific to the cells of this tumor are used. These drugs disrupt the masking of cancer cells that prevents their recognition and destruction by the patient's immune cells. As a result, the anti-tumor activity of the patient's immune system is stimulated.

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How the Disease is Diagnosed

Comprehensive diagnostic examinations in Israeli clinics take no more than three days.


First Day

During the initial consultation, the treating oncologist reviews the patient's medical history, existing medical documentation, conducts a physical examination, and orders necessary tests.


Second Day

Completion of the ordered tests, which include:

  • complete blood count and biochemical blood tests;
  • blood test for specific tumor markers;
  • gastroscopy;
  • biopsy;
  • imaging studies (CT, PET-CT, MRI);
  • endoscopic ultrasound.


Third Day

After the tests, a medical council consisting of the treating oncologist and several specialized experts reviews the results, makes a final diagnosis, and develops a treatment plan.

How Much Does Treatment Cost

The final amount is determined after the patient undergoes diagnostic examinations and a treatment plan is prescribed. On average, the cost of treatment in Israel is 30-50% lower than in comparable Western European and American clinics.

Advantages of Treatment in Israel

  • High qualifications and experience of oncologists, many of whom are recognized worldwide.
  • Accurate diagnostics on the latest equipment.
  • Application of innovative treatment methods.
  • Professional execution of endoscopic and laparoscopic surgeries.
  • Affordable prices.

Recovery from squamous cell carcinoma of the esophagus is possible; the main thing is not to waste time and to start treatment as soon as possible. Therefore, do not hesitate, choose a clinic, and trust your health to top-class specialists.

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