Sourasky Oncology Center: multidisciplinary teams, organ-preserving surgery, and targeted therapy
At the state medical center Ichilov (Sourasky) in Tel Aviv, breast cancer treatment is conducted at the Sourasky Institute of Oncology — the largest in Israel. Here, patients are simultaneously managed by a multidisciplinary team: oncologist-mammologist, surgeon, radiotherapist, pathologist, geneticist, reconstructive plastic surgeon, and psycho-oncologist. This format allows for a complete diagnostic cycle to be completed within 5–7 working days and to receive a written treatment protocol agreed upon by all specialists.
Diagnosis relies on digital 3D mammography (tomosynthesis), ultrasound with elastography, MRI of the breasts with contrast, image-guided core biopsy, and molecular genetic profiling of the tumor. To assess the risk of recurrence in hormone-dependent tumors, tests such as Oncotype DX and Prosigna are used, and for hereditary forms, analysis of BRCA1/BRCA2 and expanded genetic panels. This allows for the avoidance of excessive chemotherapy where it does not improve prognosis.
Treatment includes breast-conserving surgeries (lumpectomy, oncoplastic resection), skin-sparing and nipple-sparing mastectomy, immediate reconstruction with an expander/implant or using the patient's own tissues (DIEP flap), intraoperative radiation therapy, modern linear and stereotactic radiotherapy. The medication arsenal includes targeted therapies (trastuzumab, pertuzumab, T-DM1, trastuzumab-deruxtecan), CDK4/6 inhibitors, PARP inhibitors, immunotherapy for triple-negative cancer, as well as hormonal therapy with side effect prevention.
This section compiles materials on breast cancer treatment at Ichilov: detailed reviews of surgical techniques and reconstruction, articles on early and genetic diagnosis, analysis of hormonal and targeted therapy, as well as clinical news and research conducted by the Sourasky center's doctors. Below are articles, diagnostic and treatment programs, as well as leading specialized doctors of the clinic.