Papillary, follicular, medullary, and anaplastic carcinomas: surgery + radioiodine + targeted therapy
Thyroid cancer is one of the few forms of oncology with a high survival rate when treated promptly, but the choice of strategy is critically important: excessive therapy for papillary microcarcinoma is as harmful as insufficient treatment for aggressive subtypes. At the Ichilov (Sourasky) Medical Center in Tel Aviv, all treatment is built around an interdisciplinary approach: an endocrinologist, endocrine surgeon, oncologist, radiologist, nuclear medicine specialist, and pathomorphologist jointly manage the patient from ultrasound to long-term follow-up.
Diagnosis at the clinic includes thyroid ultrasound with TI-RADS assessment, ultrasound-guided fine-needle aspiration biopsy with molecular analysis of Bethesda III–IV nodules (ThyroSeq/Afirma panels), scintigraphy with ¹²³I or technetium, calcitonin in suspected medullary cancer, and PET-CT with F-18-FDG for aggressive forms. Determining the histological subtype and molecular profile (BRAF V600E, RET, NTRK, ALK) directly dictates the extent of surgery and subsequent treatment.
Surgical arsenal: total and subtotal thyroidectomy with central or lateral neck lymphadenectomy, minimally invasive access (mini-invasive and robot-assisted thyroidectomy), organ-preserving interventions for microcarcinomas, transesophageal access (TOETVA) — without an incision on the neck. After surgery for high-risk tumors, radioiodine ablation (¹³¹I) is performed, and for iodine-refractory forms — targeted therapy (lenvatinib, sorafenib, selpercatinib, cabozantinib, larotrectinib) and clinical trials of new drugs.
This hub brings together articles on all histological types (papillary, follicular, medullary, anaplastic, Hurthle cell carcinomas), protocols for radioiodine therapy and targeted therapy, as well as leading endocrine surgeons and oncologists at Sourasky.
World-renowned specialist in the treatment of ENT diseases. Heads the Department of Otorhinolaryngology and Surgical Treatment of the Neck and Head at the largest Israeli center, Ichilov-Sourasky. Professor specializes in general otorhinolaryngology, head and neck tumor surgery…
Treatment methods, clinical cases, leading physicians.
Ориентировочные цены на диагностику, ПЭТ-КТ, химио- и иммунотерапию, операции и ТКМ в государственном медцентре Ихилов (Сураски), Тель-Авив, и из чего складывается программа под ключ.
Read moreleading otolaryngologist, ENT surgeon
Read moreDeputy Head of the Otorhinolaryngology Department
Read moreEndocrinologist
Read moreThe thyroid gland is located in front of the larynx, at the upper part of the trachea. In the body, this gland is the largest. Its task is to produce thyroxine and calcitonin, which are involved in many metabolic processes, development, and the normal functioning of the nervous system, skin, hair, and muscular system. Doctors in Israel have successfully treated various disorders of the thyroid gland for many years, regardless of their genesis.
Read moreAt the Tel Aviv Ichilov clinic, an advanced technique for thyroidectomy – the removal of the thyroid gland – has been implemented, the main advantage of which is the complete absence of any incisions, and therefore, scars on the skin of the neck. This new approach not only achieves an excellent cosmetic result of the surgery but also shortens the rehabilitation period and the patient's stay in the hospital.
Read moreIsrael's leading position in endocrinology is based on the use of advanced technologies and scientifically validated protocols. Ichilov Clinic demonstrates this by applying an exclusively personalized approach to each case of hyperthyroidism: high-precision diagnostics are used here to determine the most optimal treatment strategy…
Read moreIn Israel, medicine is renowned not only for its high level of professionalism but also for the use of cutting-edge approaches to diagnosis and treatment, making it one of the most advanced in the world. Here, complex diseases in the field of endocrinology, including hypothyroidism, are effectively treated using advanced technologies and the latest therapeutic methods.
Read moreEndocrinologist
Read moreMedical tourism is extremely popular, attracting patients from around the world with its high level of medical care. Many choose Israel primarily due to its unique combination of advanced treatment methods and an individualized approach to each case.
Read moreEndocrinologist
Read moreIsraeli endocrinologists have extensive experience in the therapy of benign tumors of the thyroid gland. The diagnostic cycle here concludes within just a few days after the patient's visit to the clinic, and upon establishing an accurate diagnosis, the patient receives a carefully outlined treatment program.
Read moreOncology is one of the priority and most developed areas of activity at the Top Ichilov clinic. Its first-class specialists, with years of experience and thousands of successfully conducted anti-cancer therapies, effectively combat even rare types of cancer, including lymphoma...
Read moreleading otolaryngologist, ENT surgeon
Read moreDeputy Head of the Otorhinolaryngology Department
Read moreHead of the Institute of Nuclear Medicine
Read moreEndocrinologist
Read more"Top Ichilov" is one of the largest and most well-known medical centers in Israel, focusing on early diagnosis and treatment of thyroid diseases. This private healthcare institution has long been addressing issues of diagnosis, surgery, therapy, and prevention of numerous diseases.
Read moreTOETVA is a modern innovative technology that ensures safety, effectiveness, and excellent results in thyroid surgery. Since its inception in 2016 and application at Johns Hopkins University, USA, the TOETVA method has gained popularity worldwide. Scientific and clinical studies, as well as tens of thousands of successful procedures performed in various countries, confirm its effectiveness. Compared to traditional methods, TOETVA has a significant advantage, allowing for the avoidance of incisions and scars on the neck during partial or total removal of the thyroid gland, nodules, or tumors (depending on their size).
Read moreEndocrinologist
Read moreEndocrinologist
Read moreOncologists at Ichilov Clinic have a high reputation in the field of diagnosis and treatment of various types of malignant pathologies. An individualized approach to each patient makes the treatment of lymphoblastic B-cell lymphoma in Israel effective and predictable. The therapy program takes into account ...
Read moreOne of the largest clinics in Israel, Top Ichilov, actively implements the most progressive developments in cancer treatment. A traditional method such as radiotherapy has recently undergone significant changes. The main principle of radiation therapy – initiating destruction processes in cancer cells through irradiation – remains unchanged.
Read moreThe competence and experience of doctors, the equipping of medical centers in Israel with modern equipment, and the implementation of innovative treatment methods into clinical practice allow for excellent results in the treatment of severe and rare oncological diseases. Esthesioneuroblastoma...
Read moreFrom all over the world, the Ichilov Medical Center attracts doctors who are experts in their fields and have extensive practical experience. The clinic provides comprehensive treatment for acral lentiginous melanoma in Israel, combining the latest advancements in surgery, chemotherapy, radiation...
Read moreleading dermatologist and oncologist
Read moreHead of the Hematology Department
Read moreTop Ichilov is among the top three most powerful clinics in Israel, specializing in high-precision diagnostics and effective treatment of all types of oncological diseases. The latest equipment, world-class specialists, and availability of experimental treatment methods make non-surgical intervention a reality in 42% of cases.
Read moreHead of the Institute of Hematology and Oncohematology
Read moreOphthalmologist, specialist in oculoplastic surgery
Read moreOne of the most informative diagnostic methods when suspecting oncological damage to any organ is a biopsy. The samples of tissue removed during the procedure are carefully examined under special microscopes, resulting in the determination of not only the nature of the tumor (benign or malignant)...
Read moreUrologist
Read moreChoosing the Ichilov clinic for the fight against stomach lymphoma provides access to world-class medical solutions and significantly increases the chances of complete recovery. High effectiveness is achieved here through the implementation of cutting-edge protocols that allow even aggressive forms of the disease to be transformed into a fully controllable state.
Read moreResearchers from the University of Pennsylvania have developed an innovative method for controlling cells using temperature. This approach could serve as a foundation for new types of cell therapy, where modified cells will respond to natural physiological changes, such as increased body temperature.
Read moreCAR-T cell therapy is a modern method in which the patient's own immune cells (T-lymphocytes) undergo genetic modification. In the laboratory, they are equipped with a chimeric antigen receptor (CAR) that targets cancer cells expressing the specific protein CD19, ...
Read moreHow the Ichilov (Sourasky) Medical Center diagnoses and treats primary and metastatic tumors of the brain and spinal cord: neuronavigation, awake craniotomy, stereotactic radiosurgery, Stupp protocol, TTFields, and clinical trials.
Read morehead of the Institute of Hematology and Oncohematology
Read moreSyngeneic transplantation refers to the transplantation of bone marrow from a genetically identical donor, or the transplantation of stem cells from identical twins. This type of transplantation is only possible between individuals who have an identical genotype.
Read moreHead of the Department of Bone and Soft Tissue Oncology
Read moreTo ensure you feel as comfortable as possible in our clinic, we provide a medical escort for free! Learn more about the details. The rapid development of medicine, especially oncology, the development and implementation of innovative therapeutic methods and drugs into clinical practice have led to remarkable successes in the treatment of lung sarcoma.
Read moreMedical engineers have developed a microfluidic device that can be used as a non-invasive tool for diagnosing multiple myeloma and monitoring the disease's progression. The innovative device has enabled researchers to detect a specific type of circulating blood cells that are associated with shorter survival times.
Read moreA hamartoma in the lung is a growth made up of cartilage-like tissue and parts of the bronchial walls. It appears as a single round, usually lobulated mass ranging from five millimeters to five centimeters in size. It typically does not grow larger. A…
Read moreThe Ichilov clinic employs leading oncologists and hematologists with significant experience in the diagnosis and therapy of oncological hematological diseases. The high qualifications of the staff and the latest medical equipment attract patients from all over the world for the treatment of immunoblastic B-cell lymphoma in Israel…
Read moreHow the Tel Aviv Ichilov (Sourasky) clinic diagnoses and treats Hodgkin lymphoma, DLBCL, follicular lymphoma, and relapses — from PET-adaptive therapy to CAR-T.
Read moreThanks to years of clinical experience and expert mastery of the most modern medical equipment, specialists in the gastroenterology department of the Top Ichilov clinic successfully and promptly diagnose and treat various diseases of the colon and intestines.
Read moreIn modern oncology, the personalized approach is reaching a new level. Results from the Australian Molecular Screening and Therapeutic (MoST) program published in March 2026 proved that to overcome rare and resistant forms of cancer, it is not enough to simply find a mutation; it is necessary to select a drug with the highest level of evidence.
Read moreResearchers have discovered why the disease returns again and again.
Read moreAt the Top Ichilov Medical Center, a comprehensive examination program has been developed for patients with gastrointestinal tract pathologies. One of the most informative methods for examining the upper parts of the digestive tract (esophagus, stomach) is esophagoscopy — an endoscopic procedure during which a special optical device (smooth tube) with a light source is inserted into the esophagus, allowing the doctor to thoroughly inspect the mucous membrane of the organ to identify any pathology.
Read moreA team of scientists from a research institute affiliated with Virginia Polytechnic Institute and State University, USA, has discovered that a gene responsible for regulating circadian rhythms represents a potential target that, when affected, could combat a deadly form of brain cancer – glioblastoma.
Read moreIsraeli medicine is undoubtedly the most advanced in the world, attributed to excellent organization of diagnostic and treatment processes, close attention to healthcare issues by government structures, excellent training of specialists, and the use of the most advanced methods. This trend extends to urology as well.
Read moreCAR-T therapy is one of the newest and most promising directions in the treatment of oncological diseases. The method involves 'training' the patient's immune cells to fight cancer. They are extracted from the blood, then modified by equipping them with special receptors that help them recognize...
Read moreIn Israel, patients can receive advanced treatment for lipid-secreting cancer due to a high level of medical expertise, modern equipment in clinics, and the use of breakthrough medications that are not available in domestic medicine. The collegial approach of doctors from different specialties ensures an optimal treatment plan for each patient, significantly improving the overall prognosis.
Read moreIn the multidisciplinary medical institution, the Top Ichilov clinic, the procedure for lymph node (sentinel) biopsy is widely accepted. Diagnosing metastases in sentinel lymph nodes is the most reliable method to determine malignant breast tumors. It is clear that lymph nodes affected…
Read moreAs is known, during a biopsy, samples of tumor tissues are collected for further research and determination of the optimal treatment method. Their role does not end there – they can be used to study various types of cancer diseases, with the aim of identifying new biomarkers, creating drugs for their treatment, and developing effective diagnostic methods.
Read moreSquamous cell carcinoma is the most common type of malignant neoplasm of the tongue, developing as a result of malignant changes in the cells of the flat epithelium. Treatment of squamous cell carcinoma of the tongue in Israel is carried out using advanced techniques that combine high effectiveness and gentle action on the patient's body.
Read moreIsrael and one of its best clinics, Top Ichilov, annually confirm their leadership positions in the field of early detection and successful treatment of tumor lesions in the gastrointestinal tract (GIT).
Read moreHead of the Oncology Center
Read moreHead of the Department of Bone and Soft Tissue Oncology
Read moreExtragonadal germ cell tumors are neoplasms of benign and malignant nature that arise due to pathological changes in embryonic cells of the reproductive glands. The reasons why these cells migrate beyond the ovaries and testes to other parts of the body are still unclear…
Read morehead of the Institute of Hematology and Oncohematology
Read moreAnswers from the international department of the Ichilov (Sourasky) clinic — on timelines, documents, payment and language.
The same multidisciplinary format for other tumor types — jump to a dedicated hub.
Hepatocellular carcinoma, cholangiocarcinoma, and liver metastases — diagnosis and therapy
Go to hubHematology-oncology, targeted therapy, CAR-T, and bone marrow transplantation
Go to hubImmunotherapy, targeted therapy, and microsurgery under the supervision of leading dermatologic oncologists.
Go to hubMultidisciplinary approach: surgery, chemotherapy, targeted therapy, and immunotherapy
Go to hubDiagnosis, da Vinci robotic surgery, radiation therapy, and targeted therapies in one center
Go to hubThoracic surgery, robotic surgeries, targeted and immunotherapy
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