Lymphoma Treatment in Israel

Professor Ella Naparstek

leading hematologist and hemato-oncologist

At the Top Ichilov clinic, oncological hematological diseases, including various types of lymphomas, have been treated successfully for a long time. The clinic has everything necessary for treating patients at different stages of the disease. High-tech equipment allows the use of the latest radiation therapy and surgical techniques, minimizing the risk of complications and increasing the effectiveness of therapy. The oncologists at the clinic are highly qualified doctors with the necessary knowledge and experience. They are skilled in innovative treatment methods and the most progressive techniques, including targeted therapy and bone marrow transplantation. These methods enable us to help even those patients who were previously considered hopeless. As a result of treatment, the cancer formation is destroyed, the spread of metastases is halted, and a stable remission is achieved. The best confirmation of the effectiveness of lymphoma treatment in Israel is the feedback from patients who have already undergone therapy courses at Top Ichilov. Patients highly appreciate the qualifications of the doctors, their competent and attentive approach to each patient. There are also many positive reviews regarding the organization of the entire process, from assistance in purchasing airline tickets to providing a Russian-speaking staff member for support.

97%

disease diagnosis

94%

of patients relieved from pain

1258

surgeries performed

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Table of Contents

Treatment Methods

Diagnosis

Prices

How Lymphoma is Treated in Israel

Thanks to ultra-precise diagnostics, doctors can accurately determine the type and degree of malignancy of the neoplasm with 100% certainty. Based on this data, a therapy program is developed. In some cases, if it is found that the neoplasm has low malignancy indicators and does not have destructive manifestations, active monitoring may be possible for some time. However, if the lymphoma is aggressive, therapy begins as soon as possible. The methods of lymphoma treatment in Israel aim for rapid normalization of hematopoiesis and preservation of the patient's bodily resources in full.

Chemotherapy. Typically, it is always included in the treatment program, as cancer cells spread quickly throughout the body via the lymphatic system, and the doctors' task is to stop this process as quickly as possible. The duration of systemic chemotherapy, the type of drugs, and their dosage are prescribed individually. The cytostatic drugs used at the Top Ichilov clinic target malignant cells, depriving them of the ability to multiply and causing their natural death. Moreover, the latest generation drugs are less toxic to the body and cause fewer complications.

Radiotherapy. If an aggressive lymphoma is detected, a course of radiotherapy is prescribed. The effect of radiation on the tumour is lethal for cancer cells: the structure of their DNA is damaged, leading to their death, and the neoplasm decreases in size or disappears completely. For radiotherapy sessions, the Top Ichilov clinic uses Novalis linear accelerators – state-of-the-art equipment. It allows for irradiating the pathological focus with an accuracy of up to 0.5 mm, while not affecting the healthy tissues surrounding the lymphoma. Radiotherapy is used in combination with chemotherapy and surgical methods.

Extracorporeal Hemosorption. To quickly restore normal blood parameters, cleanse it of toxins and cancer cells, a blood purification method may be used. Doctors take a certain amount of blood, which is then purified in laboratory conditions, enriched with healthy donor blood cells (platelets and red blood cells), and then reintroduced into the bloodstream.

Bone Marrow Transplantation. This is performed in severe cases when the process of blood cell production by the bone marrow is disrupted due to the disease or high-dose chemotherapy. At the Top Ichilov clinic, the procedure is performed according to modern standards, improving treatment forecasts by 40%. Donor biomaterial or the patient's own bone marrow may be used (autologous transplantation avoids rejection reactions to foreign bone marrow). The choice of transplantation type depends on the patient's condition (allogeneic transplantation is performed in the relapse stage) and age (autologous transplantation cannot be performed on young children).

Targeted Therapy. This innovative therapy can tackle the disease even when the tumour does not respond to standard treatment. For example, it may be prescribed to patients whose chemotherapy course has not yielded significant results. This type of treatment is characterized by the targeted destruction of only cancer cells, without harming normal ones. The drugs identify abnormal cells and attack them directly. Currently, targeted therapy can be used at various stages of lymphoma, in combination with other methods.

Removal using Minimally Invasive Techniques. If the tumour is small and has clear boundaries, it can be removed. Previously, a full operation was performed for this, but now at the Top Ichilov clinic, less traumatic treatment is possible. The procedure for destroying the neoplasm can be performed on an outpatient basis without hospitalization. The patient does not experience blood loss or complications, and recovery takes a short time. Two main minimally invasive techniques are used:

• Photodynamic Therapy. A substance that is highly sensitive to light is introduced into the area of the tumour. Then, a laser beam is directed at the cancer focus. Under the influence of the beam, the tissues containing the photosensitizer quickly heat up to a temperature at which tissue destruction occurs. The photosensitizing substance is subsequently naturally eliminated from the body.
• Cryodestruction. This method uses the properties of ultra-low temperatures to rapidly destroy human tissues. Using a cryoneedle, under the supervision of equipment, a substance with a temperature reaching two hundred degrees below zero is introduced into the pathological focus.

Surgical Treatment. When surgical removal of the neoplasm is necessary, the Top Ichilov clinic employs gentle endoscopic techniques. These involve minimal surgical incisions, which minimizes blood loss and postoperative risks. Surgeries are performed by surgeons with the experience and skills necessary for conducting endoscopic operations.

Diagnosis of Lymphoma in Israel

At Top Ichilov, examinations are conducted according to modern standards and methods, which allow for the precise determination of the presence of a malignant process, the type of lymphoma, and the stage. 100% accurate diagnosis is performed even at the earliest stages when there are no external manifestations of the disease.

For the convenience of foreign patients, diagnostics are conducted within three days, according to a pre-agreed schedule. This saves patients from the need to wait a long time for their turn in the diagnostic office.

First Day

The hemato-oncologist examines and consults the patient. The doctor studies the medical history and clarifies the list of diagnostic studies.

Second Day

All diagnostic procedures are carried out:

• Biopsy with subsequent laboratory examination
• Myelogram – examination of bone marrow
• Blood tests – biochemical, for tumor markers, etc.
• CT
• MRI
• PET-CT – detection of secondary tumor foci
• X-ray.

Third Day

A council is convened, attended by specialized doctors. They analyze the examination data and develop a therapy program.

For lymphoma patients, consultations via Skype are possible – this option is chosen by those patients who are undergoing treatment at another clinic and would like to conduct an independent assessment of the adequacy of the therapy being conducted at home. Online consultation is a budget-friendly option for those who cannot come to Top Ichilov in person, as well as for those who would like to meet the doctor who will be treating them before their arrival. To conduct a consultation, it is necessary to send a request through the website, indicating the reason for the inquiry, contact details, and preliminary diagnosis. Copies of test data and medical records should also be sent so that the Israeli expert can analyze them and provide their opinion on the diagnosis and the effectiveness of the ongoing treatment. Following the online consultation, the patient receives a doctor's conclusion with recommendations for treatment.

Lymphoma Treatment in Israel: Prices

Advantages of Treatment at Top Ichilov

• Accurate diagnosis at any stage
• Choice of gentle therapy methods with minimal complications
• Highly effective and innovative therapy methods
• Opportunity to receive treatment from a world-class hemato-oncologist
• Competitive prices.

To learn more about organizing treatment at Top Ichilov, simply fill out the application – our consultant will contact you shortly.