This section is dedicated to the diagnosis and treatment of leukemia at the state medical center Ichilov (Sourasky) in Tel Aviv — the largest hospital in Israel and one of the leading hematology-oncology centers in the Middle East. Here, all major forms of the disease are monitored and treated: acute lymphoblastic (ALL) and acute myeloid (AML) leukemias, chronic lymphocytic (CLL) and chronic myeloid (CML) leukemias, as well as rare and aggressive variants in children and adults.
The examination begins with a comprehensive blood analysis, aspiration and biopsy of the bone marrow, immunophenotyping by flow cytometry, cytogenetics, and molecular diagnostics (FISH, PCR, NGS panels). Accurate determination of subtype and mutation profile allows for the selection of a protocol that complies with the international guidelines of NCCN and ELN, avoiding time wasted on ineffective regimens.
The clinic's arsenal includes modern polychemotherapy, targeted therapies (tyrosine kinase inhibitors for CML, BCL-2 and FLT3 inhibitors for AML, BTK inhibitors for CLL), monoclonal antibodies and bispecific antibodies (blinatumomab, inotuzumab), immunotherapy, as well as CAR-T cell therapy and allogeneic bone marrow transplantation from related, unrelated, or haploidentical donors. The hematopoietic stem cell transplantation department at Ichilov is among the largest in the country and works closely with the international donor registry.
Treatment is managed by an interdisciplinary team: hematologist-oncologists, transplantologists, infection specialists, intensivists, pediatric oncologists, and psycho-oncologists. For international patients, the international department organizes consultations in Russian, second opinions on slides and images, hospitalization, and logistics. Below are articles and programs on the topic, as well as specialized doctors who can be consulted.