Pyonephrosis is a purulent kidney disease characterized by tissue necrosis and progressive suppression of the organ's functional activity. Typically, the pathology develops at the terminal stage of acute urinary tract inflammation. Treatment of pyonephrosis in Israel involves surgically removing the affected kidney using advanced gentle methods in conjunction with effective medication therapy and a comprehensive rehabilitation course. Following the prescribed treatment and subsequent adherence to medical recommendations improves prognosis, alleviates symptoms, and significantly reduces the likelihood of complications in more than 90% of patients.
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he diagnosis of the disease is complicated by the combination of its symptoms with manifestations of the underlying pathology against which pyonephrosis developed. The diagnostic departments of Israeli medical centers are equipped with the latest technology, allowing for the rapid identification of the disease, establishing its characteristics, and assessing the overall condition of the patient. Comprehensive examinations also confirm the primary diagnosis made for the foreign patient in their home country, which often turns out to be incorrect. Patient reviews confirm the effectiveness of treatment, reasonable costs of services provided, and comfortable conditions in the clinic.
Treatment Methods for the Disease
Pyonephrosis, also known as purulent kidney, is a serious urological disease, the absence of timely adequate treatment for which leads to disability in more than 65% of patients. This pathology often develops as one of the most severe complications of kidney diseases, occurring in women approximately 4-5 times more often than in men.
The following causes of pyonephrosis are identified:
- infection of the urinary tract by pathogenic microorganisms — pyonephrosis occurs in the final stages of pyelonephritis, cystitis, kidney tuberculosis, and a number of other kidney infectious diseases in cases of incorrectly prescribed antibacterial treatment or non-compliance by the patient with the doctor's prescriptions;
- urolithiasis — formed stones hinder the free passage of urine, worsen hemodynamics, leading to significant suppression of immunity and an increased likelihood of infection;
- placement of a urinary catheter — the disease may develop as a result of using a non-sterile catheter or injuring the urinary tract during its placement;
- congenital and acquired pathologies of the urinary system (duplication of ureters and kidneys, kidney prolapse, and others).
Open and closed forms of pyonephrosis are distinguished. In the first case, products of purulent inflammation enter the urine, being excreted along with it through the ureter. In this case, the urine analysis shows an increased content of leukocytes. In the closed form, the focus of inflammation is surrounded by a dense capsule made of connective tissue elements, which prevents the outflow of urine and retains pus. Since urine is only excreted from the unaffected kidney, laboratory tests cannot detect inflammation. In the absence of timely adequate treatment, the closed form can transform into an open one.
In the first days of the disease, the patient's condition is satisfactory, with aching pains in the lumbar region and a subfebrile temperature. As the pathology progresses, the condition worsens: the temperature reaches 40-41℃, symptoms of severe general intoxication appear, and intense pain occurs, up to renal colic. One of the most characteristic symptoms of pyonephrosis is cloudy urine due to the presence of tissue breakdown products. Cloudy urine is observed in the open form of the disease, which is also characterized by weak expression or absence of signs of intoxication.
In cases of kidney damage and absence of signs of ureter involvement, complete removal of the affected kidney — nephrectomy — is indicated. The operation is performed laparoscopically or by open method. The advantages of laparoscopy include a low probability of damage to healthy tissues and the development of complications, as well as a short postoperative period. If the initial cause of the purulent inflammation is stenosis of the ureteral lumen, nephroureterectomy — removal of the kidney along with the ureter — is performed. This is also done laparoscopically or by open method.
The preparation period for nephrectomy takes, on average, a week and requires hospitalization of the patient. In addition to comprehensive laboratory and instrumental examinations, consultations with a nephrologist, therapist, cardiologist, and several other narrow-profile specialists are necessary. Urgent surgery is required in cases of acute closed form of the disease, as there is a high probability of capsule damage and pus entering the abdominal cavity, leading to peritonitis and sepsis.
In cases of severe patient condition, presence of serious comorbidities, impaired normal function of the unaffected kidney, or diagnosis of bilateral pyonephrosis, surgical intervention is performed in two stages. Initially, a nephrostomy is placed (an artificial channel between the kidney and the skin surface for urine drainage), allowing for the drainage of the focus of purulent inflammation. Simultaneously, antibiotic therapy, detoxification, and plasmapheresis are prescribed to the patient. After stabilization of the condition, nephrectomy is performed.
Diagnostic Methods for the Disease
To establish an accurate diagnosis and prescribe a treatment regimen, a patient examination is required, which takes no more than three days in Israeli clinics.
Upon admission to the clinic, the patient is directed to a consultation with a leading urologist. During the appointment, the doctor reviews the medical history, existing results of previous studies, and medical conclusions. Upon palpation, tenderness and enlargement of the affected kidney are noted, and its mobility is significantly restricted. At the final stage of the consultation, the urologist prescribes the necessary types of examinations.
Performing the prescribed diagnostic procedures:
- Laboratory tests of urine and blood — the presence of an inflammatory process is indicated by cloudy urine sediment, the presence of a large number of leukocytes, protein, and mucus. Inflammation also alters the blood cell composition: an increased number of leukocytes and elevated ESR levels. Blood biochemistry shows high levels of creatinine and urea. To accurately identify the pathogen of pyonephrosis, necessary for selecting effective antibiotics, a bacterial culture of urine is performed.
- Ultrasound examination (US) of the kidneys — an informative method that allows for the identification of the focus of inflammation, establishing its characteristics, and assessing the activity of urodynamics in kidney structures.
- Radiological examination of the kidneys (plain urography, CT).
- Angiography of the kidney vessels.
- Nephroscintigraphy.
The results of the studies are reviewed by a council consisting of a urologist and narrow-profile specialists. After studying the obtained data, the doctors collectively establish a diagnosis and develop a treatment program.
How Much Does Treatment of the Disease Cost
The cost of therapy is one of the questions that remains relevant for medical tourists. Undergoing treatment in Israeli clinics allows patients to save about 30% of the amount required in Western European countries and approximately 50% of the funds needed in the USA.
Advantages of Treatment in Israel
- Doctors among the leading specialists in this field of medicine worldwide.
- Modern material and technical base.
- Perfect mastery of advanced surgical treatment methods.
- Comfortable conditions.
- Affordable prices.
Timely completion of a comprehensive therapeutic course will lead to recovery, restoration, and return to normal life. Do not waste time, contact your chosen Israeli clinic and start treatment as soon as possible.