Autologous transplantation is the process of collecting stem cells from the patient's bone marrow during remission for further preservation through subsequent cryopreservation. Currently, in addition to bone marrow, stem cells obtained from the patient's peripheral blood are widely used.
Reasons
Typically, autologous transplantation is prescribed after chemotherapy to reduce the duration of hematopoietic suppression that occurs after a course of prolonged chemotherapy. Autologous transplantation is an integral part of the treatment for bone marrow diseases, such as leukemia, lymphoma, multiple myeloma, and aplastic anemia. This type of transplantation is one of the safest forms of bone marrow transplantation, as the risk of rejection by the body is excluded, since the donor is the patient themselves.
The most optimal and comfortable conditions for safe transplantation are created specifically in Israel. If you want to undergo autologous transplantation with the least risk, it is advisable to consult Israeli specialists.
Autologous transplantation is particularly relevant when there is no possibility of performing a syngeneic transplantation, and the risk of performing an allogeneic transplantation is exceedingly high due to the individual characteristics of the patient's body. Israeli specialists have developed a whole range of innovative methods for collection, purification, and storage of bone marrow up to the moment of transplantation.
The collection of bone marrow for extracting stem cells typically occurs surgically. The edge of the hip joint (iliac crest) is punctured, after which the bone marrow is collected. After collection, the material undergoes a series of laboratory tests that allow for determining the number of stem cells in the given volume of bone marrow.
There is also the collection of stem cells through apheresis, which is when stem cells are extracted from the patient's blood using a "blood cell separator." Rarely does the extraction of stem cells through apheresis occur in one procedure; typically, several apheresis procedures are required to obtain the necessary amount of stem cells.
The collected cells are transplanted by introducing them into the patient's bloodstream or directly into the affected organ.
The entire process of both collection and transplantation is performed under local anesthesia.
Highly qualified Israeli doctors carry out the entire transplantation process using the latest high-tech equipment, which minimizes the risk of complications to a negligible minimum.
Years of positive experience and extensive practice in treating oncological diseases allow Israeli specialists to provide treatment at a high level and annually achieve the highest percentage of complete remission in cancer patients.