Professor Ella Naparstekleading hematologist and hemato-oncologist
Myelofibrosis is a specific disease of the bone marrow (also known as subleukemic myelosis), often leading to the development of osteomyelosclerosis. The disease causes the development of fibrous tissue in the bone marrow, resulting in impaired hematopoietic functions. Treatment of subleukemic myelosis abroad has been conducted for several decades, while in the CIS countries, this disease is rarely diagnosed correctly and is amenable to therapy. The experience of the best hematologists in the country practicing at Top Ichilov allows for significant success in the treatment of chronic subleukemic myelosis in Israel and its associated diseases.
The modern technical equipment of the clinic allows for treatment in accordance with the highest global standards and achieving significant success in a short time. Diagnosis of chronic subleukemic myelosis in Israel is carried out within a few days, allowing for the quickest possible start to treatment.
Doctors at the clinic participate in various international conferences and scientific research, constantly improving their qualifications and refining existing methods of treating myelofibrosis in Israel. Leading hematologists and oncohematologists in the country save the lives of thousands of patients from around the world every year.
Rehabilitation conditions at Top Ichilov receive special attention. Certified psychologists, physiotherapists, and dietitians work with the patient. Their work gives the patient a chance to return to a normal lifestyle as quickly as possible.
Each patient receives comprehensive support and professional care from the medical staff, who make every effort to maintain comfortable conditions during their stay at the clinic.
Treatment Methods for Myelofibrosis in Israel
Medication treatment. By using individually tailored pharmaceutical preparations, doctors manage to stabilize the patient's condition, minimize current symptoms of the disease, and avoid potential complications. The primary task of the doctors is to treat anemia caused by myelofibrosis. Chemotherapeutic agents may also be prescribed to destroy mutated cells and prepare the patient for a bone marrow transplant.
Blood transfusion helps manage critical anemia when medication treatment is ineffective. Donor blood is selected with special care, undergoing several stages of laboratory testing to avoid complications caused by incompatibility with the patient's body.
Radiation therapy is one of the effective methods for destroying mutated cells, often preceding the bone marrow transplant procedure. The capabilities of radiation therapy in Israel are much broader than in clinics in the CIS countries, as Israel uses the latest radiology equipment, such as advanced linear accelerators TrueBeam and Novalis, which provide targeted impact on the affected tissues.
Bone marrow transplantation. This is one of the most reliable yet labor-intensive methods for treating myelofibrosis and osteomyelosclerosis in Israel. The Top Ichilov clinic is one of the few clinics in the world that has created the necessary conditions for this operation. Bone marrow transplantation in Israel is carried out in several stages. After preliminary examinations, the patient is assigned several courses of polychemotherapy and radiation therapy, which allows for the elimination of all mutated cells from the body.
One of the most critical stages of treatment is selecting suitable donor material. Bone marrow from the patient's closest relative is most commonly used. The patient's own bone marrow, collected during a stable remission and preserved under special conditions, may also be used.
The transplant occurs just like a regular blood transfusion, through intravenous infusion of the material. During the treatment, the patient is placed in a special sterile room, where there is no risk of infectious contamination due to their compromised immune system from chemotherapy. The bone marrow reaches its destination and engrafts within 2-3 weeks. Throughout this time, the patient remains hospitalized under constant medical supervision.
Surgical treatment of a symptomatic nature. Myelofibrosis often causes critical enlargement of the spleen (splenomegaly). To address this issue, a laparoscopic surgery (splenectomy) may be performed, which helps reduce the symptoms of the disease and avoid severe anemia. Thanks to the use of modern microsurgical instruments, the patient tolerates the surgical intervention well, and their life is not threatened by complications typical of classical intra-abdominal surgeries.
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Accurate Diagnosis – The Foundation of Successful Treatment of Subleukemic Myelosis in Israel
Day One – Consultation with a Leading Specialist in Israel
Upon arrival in Israel, the patient is met at the airport by a coordinator who accompanies them to the clinic. This same coordinator stays with them throughout the treatment course in Israel and acts as a translator if necessary.
First, the patient is directed to a consultation with a hematologist. The doctor thoroughly collects the medical history, clarifies the circumstances of the disease onset, and conducts a physical examination.
All research results brought are sent for mandatory review and are not re-ordered if their quality is confirmed. Unfortunately, nearly 40% of research results conducted in hospitals in the CIS countries turn out to be erroneous.
Based on the information obtained, the doctor prescribes a full range of necessary diagnostic tests and explains how to prepare for them correctly.
Day Two – Diagnosis
Correct and timely diagnosis of myelofibrosis in Israel is carried out using the following methods:
- laboratory blood tests, including genetic testing, which allow determining the degree of disease proliferation and the nature of accompanying complications;
- ultrasound examination of the abdominal organs;
- computed tomography;
- bone marrow puncture, for subsequent examination of cerebrospinal fluid;
- bone marrow trepanobiopsy – allows determining the presence of scar-fibrous tissue in it.
If necessary, the doctor may prescribe additional tests and studies that will provide a more complete picture of the disease.
Day Three – Treatment Plan
To develop a treatment plan at Top Ichilov, a special commission of specialists is formed, who collectively analyze the results of the diagnostic tests conducted. Teamwork allows doctors to adopt the optimal treatment plan for the patient and achieve maximum objectivity. All decisions are made in the direct presence of the patient. Thus, the patient understands the basis on which certain procedures are prescribed, how they will be carried out, and how long the treatment will last.
Cost of Treatment for Subleukemic Myelosis (Myelofibrosis) in Israel
The cost of treating myelofibrosis in Israel is nearly 50% lower than in clinics of similar level in Germany and the USA. The price for myelofibrosis treatment in Israel is determined based on several factors, such as the level of disease proliferation and the presence of accompanying complications.
To obtain information about the cost of medical services at Top Ichilov clinic, please leave a request by filling out the form on the website. A representative from our call center will contact you shortly to answer all your questions.
| Type of Service | Prices |
|---|---|
| Treatment of Myelofibrosis | from $7440 to $74400 |
| Consultation conducted by world-class expert Professor Ella Naparstek |
Advantages of Treating Subleukemic Myelosis Abroad
Israel is a recognized center of global medical tourism, which is due to the following factors:
- the highest level of knowledge and practical skills in treating a wide range of diseases of varying complexity makes Israeli doctors true professionals in their field;
- The Top Ichilov clinic is equipped with the most modern and expensive medical technology, which allows doctors to perform complex surgeries and implement treatment using innovative methods;
- The medical staff of the clinic provides highly professional medical support and care, which is necessary for patients undergoing inpatient treatment. Thanks to the cohesive work of the clinic's team, aimed at the patient's swift recovery, the clinic client is surrounded by comprehensive care and attention;
- Comfortable conditions for treatment are ensured by the international department of Top Ichilov, which assists the patient in resolving all domestic and organizational issues;
- Professional psychological assistance, which works with the patient throughout the treatment period at the clinic, helps them cope with all stages of treatment and return to normal life as quickly as possible;
- The Top Ichilov clinic provides its patients with the best conditions for rehabilitation. The patient maintains remote communication with doctors and consultants from the clinic even after returning home.