Endocrine factors account for approximately 40% of all infertility causes. Hormonal imbalances can affect both female and male fertility. The Top Ichilov Clinic provides qualified treatment for endocrine infertility in Israel using modern therapeutic protocols.
Experienced reproductive specialists at Top Ichilov utilize a wide range of proven and safe hormonal agents to help restore fertility. They select medications on an individual basis only after conducting a thorough medical examination and carefully studying the results of all necessary diagnostic tests.
After developing a therapeutic protocol, the reproductive specialist educates the patient on the correct administration of the medication to achieve maximum effect. Some medications are taken orally, while others are administered via injection. The staff at Top Ichilov Clinic will also assist with other aspects of infertility treatment, including lifestyle modification and emotional support.
How Endocrine Infertility is Treated
The choice of treatment strategy depends on the specific type of endocrine disorders, age, and the patient's pregnancy and childbirth history.
Polycystic Ovary Syndrome (PCOS). The cause of PCOS involves several hormonal disorders that mutually influence and exacerbate each other. Increased androgens in the blood lead to the appearance of numerous follicles that do not mature and do not exit the ovary. At Top Ichilov, medical treatment for PCOS involves ovulation stimulation. Surgical treatment is rarely performed due to its low effectiveness, but laparoscopic dissection or laser perforation may be conducted if the ovarian capsule is thick.
Hypothalamic-Pituitary Insufficiency or Dysfunction. The pituitary gland produces two hormones responsible for stimulating monthly ovulation – FSH and LH. Excessive physical or emotional stress, very high or very low body weight, as well as rapid weight gain can disrupt the production of these hormones and affect ovulation. Hormone therapy is used at Top Ichilov to treat insufficiency. In cases of dysfunction, additional medical and physiotherapeutic stimulation of ovulation is applied.
Corpus Luteum Insufficiency. The corpus luteum is a temporary gland that appears after ovulation. If it produces insufficient amounts of the hormone progesterone, the egg cannot implant in the uterine wall. There is also an increased risk of miscarriage. Corpus luteum insufficiency at Top Ichilov is treated with hormones on an individual basis. This is an effective and safe treatment for endocrine infertility in Israel, with consistently positive reviews.
Thyroid Dysfunction. If the thyroid gland does not produce sufficient amounts of iodine-containing hormones, there is a risk that the hypothalamus will begin to secrete TRH excessively. TRH, in turn, stimulates the production of prolactin, which may prevent ovulation. If a patient is found to have high levels of prolactin, the doctor will investigate the cause and ways to address the thyroid dysfunction.
Premature Ovarian Insufficiency. This disorder is usually caused by an autoimmune reaction, genetic factors, or chemotherapy. The ovaries no longer produce oocytes, leading to decreased estrogen production before the age of 40. Some women may benefit from hormone therapy, while others will need to utilize assisted reproductive technologies.
Hypothalamic-Pituitary Infertility in Men. Men may have abnormally low levels of pituitary hormones FSH and LH, which are necessary for stimulating sperm production and development. These patients typically respond well to infertility treatments with medications containing FSH, LH, and hCG. These medications replenish the deficiency of necessary hormones and promote normal sperm production. This is an effective treatment for endocrine infertility in Israel, with costs significantly lower than artificial insemination.
While most couples are able to restore their fertility through hormone therapy, others may need to try assisted reproductive techniques. These include in vitro fertilization (with or without donor eggs) and intracytoplasmic sperm injection (ICSI). All these procedures have different success rates based on the woman's age and the couple's infertility causes. Nevertheless, the success rate of artificial insemination in Israeli clinics is among the highest in the world.
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How Endocrine Infertility is Diagnosed
There are reasons you may need an independent expert opinion. You may not be sure that the diagnosis is correct, or you may want to learn about alternative treatment options. In such cases, the "second opinion" service provided by Israeli doctors can help.
To consult with a doctor, you no longer need to travel to Israel and spend extra money. With the "video consultation" option, you can speak with a doctor at a convenient time for you and get answers to all your questions. This service allows you to avoid paying for the first in-person consultation (if needed).
Registration at the clinic, consultative services, and diagnostic examinations at Top Ichilov will take no more than three days.
Day 1: Consultation with a Reproductive Specialist
During the first appointment, the doctor will conduct a physical examination of the patient, analyze the results of existing tests, compile a medical history, and prescribe additional diagnostic tests.
Day 2: Diagnostic Procedures
The primary goal of the doctor in diagnosing female infertility is to determine the presence of ovulation. The following tests may be ordered:
- Ovulation Detection. Ovulation is confirmed using basal temperature charts, functional tests, blood hormone tests, and ultrasound.
- Ovarian Function Study. The goal is to determine hormone functioning during the ovulation cycle. This involves measuring levels of follicle-stimulating hormone and estradiol, conducting ultrasound (to confirm ovulation), and blood tests for inhibin B levels.
- Luteal Phase Study. Levels of progesterone and other hormones are determined, and in some cases, an endometrial biopsy is performed.
- Hormonal Tests. Levels of LH, FSH, estradiol, progesterone, prolactin, free T3, total testosterone, free testosterone, DHEAS, androstenedione, and other hormones will be examined.
Day 3: Treatment Assignment
After all tests are completed, your treating physician will present the results at a medical board meeting. Physicians from various specialties will jointly make a final diagnosis and choose the most appropriate treatment strategy.
Treatment of Endocrine Infertility in Israel: Price
Since endocrine disorders affecting fertility are diverse, the methods of treatment also vary significantly. Accordingly, this affects the price of medical services. However, the cost of treatment in Israel will be 30-50% lower than in reproductive clinics in the USA and Western Europe.
Why Choose Top Ichilov
- Fast and quality diagnostics based on powerful laboratories
- A wide range of safe medications
- Modern hormone therapy protocols
- The possibility of utilizing assisted reproductive techniques
- Comprehensive medical and emotional support for patients