Endocrine factors account for approximately 40% of all infertility causes. Moreover, hormonal imbalances can affect both female and male fertility. Top Ihilov Clinic provides qualified treatment for endocrine infertility in Israel using modern therapeutic protocols.
Experienced reproductive specialists at Top Ihilov use a wide range of proven and safe hormonal medications that help restore fertility. They select medications on an individual basis only after conducting a thorough medical examination and carefully studying the results of all necessary diagnostic tests.
After developing a therapeutic protocol, the reproductive specialist teaches the patient the correct way to take the medication to achieve maximum effect. Some medications are taken orally, while others are administered by injection. The staff at Top Ihilov Clinic will also assist with other aspects of infertility treatment, including lifestyle modification and emotional support.
How Endocrine Infertility is Treated
The choice of treatment strategy depends on the specific type of endocrine disorders, age, and the patient's pregnancy and childbirth history.
Polycystic Ovary Syndrome (PCOS). The cause of PCOS is several hormonal disorders that mutually influence and enhance each other. Increased androgens in the blood lead to the appearance of many follicles that do not mature and do not leave the ovary. At Top Ihilov, medication treatment for PCOS involves ovulation stimulation. Surgical treatment is rarely performed due to its low effectiveness, but in cases of thick ovarian capsules, laparoscopic dissection or laser perforation may be carried out.
Hypothalamic-Pituitary Insufficiency or Dysfunction. The pituitary gland produces two hormones responsible for stimulating monthly ovulation – FSH and LH. Excessive physical or emotional stress, very high or very low body weight, as well as rapid weight gain can disrupt the production of these hormones and affect ovulation. Hormone therapy is used at Top Ihilov to treat insufficiency. In cases of dysfunction, additional medication and physiotherapeutic stimulation of ovulation are applied.
Corpus Luteum Insufficiency. The corpus luteum is a temporary gland that appears after ovulation. If it produces insufficient amounts of the hormone progesterone, the egg cannot implant in the uterine wall. There is also an increased risk of miscarriage. Corpus luteum insufficiency at Top Ihilov is treated with hormones on an individual basis. This is an effective and safe treatment for endocrine infertility in Israel, with consistently positive reviews.
Thyroid Dysfunction. If the thyroid gland does not produce enough iodine-containing hormones, there is a risk that the hypothalamus will begin to secrete TRH excessively. TRH, in turn, stimulates the production of prolactin, which may lead to anovulation. If a patient is found to have high levels of prolactin, the doctor will seek the cause and ways to address the thyroid dysfunction.
Premature Ovarian Insufficiency. This disorder is usually caused by an autoimmune reaction, genetic factors, or chemotherapy. The ovaries no longer produce oocytes, leading to decreased estrogen production before the age of 40. Some women may benefit from hormone therapy, while others will need to utilize assisted reproductive technologies.
Hypothalamic-Pituitary Infertility in Men. Men may have abnormally low levels of pituitary hormones FSH and LH, which are necessary for stimulating sperm production and development. These patients typically respond well to infertility medications containing FSH, LH, and hCG. These medications replenish the deficiency of necessary hormones and promote normal sperm production. This is an effective treatment for endocrine infertility in Israel, with costs definitely lower than artificial insemination.
While most couples manage to restore their fertility through hormone therapy, others may need to try assisted reproductive techniques. These include in vitro fertilization (with or without donor eggs) and intracytoplasmic sperm injection (ICSI). All these procedures have different success rates based on the woman's age and the couple's infertility causes. Nevertheless, the success rate of artificial insemination in Israeli clinics is among the highest in the world.
How Endocrine Infertility is Diagnosed
There are reasons why you may need the opinion of an independent expert. You may not be sure that the diagnosis is correct, or you may want to learn about alternative treatment options. In such cases, the "second opinion" service provided by Israeli doctors can help you.
To consult with a doctor, you no longer need to travel to Israel and spend extra money. With the "video consultation" option, you can talk to a doctor at a convenient time for you and get answers to all your questions. This service allows you not to pay for the first in-person consultation with the doctor (if needed).
Registration at the clinic, consulting services, and diagnostic examinations at Top Ihilov will take no more than three days.
Day 1: Consultation with a Reproductive Specialist
During the first appointment, the doctor will conduct a physical examination of the patient, analyze the results of already available tests, compile a medical history, and prescribe additional diagnostic tests.
Day 2: Diagnostic Procedures
The primary goal of the doctor when diagnosing female infertility is to determine the presence of ovulation. The following tests may be prescribed for this purpose:
- Ovulation Detection. Ovulation is confirmed using basal temperature charts, functional tests, hormone blood tests, and ultrasound.
- Ovarian Function Study. The goal is to determine the functioning of hormones during the ovulation cycle. This involves measuring levels of follicle-stimulating hormone and estradiol, performing ultrasound (to confirm ovulation), and blood tests for inhibin B levels.
- Luteal Phase Study. Levels of progesterone and other hormones are determined, and in some cases, an endometrial biopsy is performed.
- Hormonal Tests. Levels of LH, FSH, estradiol, progesterone, prolactin, free T3, total testosterone, free testosterone, DHEAS, androstenedione, and other hormones will be examined.
Day 3: Treatment Assignment
After all tests are completed, your treating physician will present the results at a medical board meeting. Doctors from various specialties will jointly make a final diagnosis and choose the most appropriate treatment strategy.
Treatment of Endocrine Infertility in Israel: Price
Since endocrine disorders affecting fertility are diverse, the methods of treatment also vary significantly. Accordingly, this affects the price of medical services. However, the cost of treatment in Israel will be 30-50% lower than in reproductive clinics in the USA and Western Europe.
Why Choose Top Ihilov
- Fast and quality diagnostics based on powerful laboratories
- A wide range of safe medications
- Modern hormone therapy protocols
- The opportunity to utilize assisted reproductive techniques
- Comprehensive medical and emotional support for patients