The last decade has been marked by the introduction of innovative treatment methods into oncology practice, characterized by high efficacy and safety for patients. Modern therapeutic methods allow for the successful removal of tumors that were previously considered inoperable. Treatment using the IRE Nano-Knife technology in Israel allows for the destruction of multiple tumors through the application of high-voltage electric current. Based on the effect of non-thermal ablation, this technology enables the removal of tumors located in areas inaccessible for surgical resection. The destruction of malignant cells is targeted, without harming adjacent nerves and blood vessels.
Recent studies have shown that the use of the IRE Nano-Knife method can achieve sustained long-term remission in many patients with advanced stages of various types of cancer. Unlike traditional methods of anti-tumor therapy, this technology is well-tolerated by patients and does not lead to complications or side effects. The equipping of Israeli clinics with modern high-tech equipment allows for rapid diagnostics and precise localization of tumors, which is essential for the successful application of the IRE Nano-Knife. The cost of treatment using this method in Israel is favorably different from the prices of American and Western European medical centers.
When is IRE Nano-Knife Used?
Patients diagnosed with oncological pathologies are interested in which diseases are treated with the IRE Nano-Knife.
The gentle therapeutic method is based on the effect of irreversible electroporation. It allows for the removal of soft tissue tumors located in close proximity to major vessels and nerves, where treatment with other methods is ineffective. IRE Nano-Knife serves as an alternative to laser and radiofrequency ablation methods. This technique is indicated for the treatment of the following types of cancer:
- Pancreatic cancer — this method allows for the removal of malignant tumors located near the vessels responsible for the blood supply to the gland, as well as tumors that have spread to these vessels. IRE Nano-Knife helps improve the patient's condition and slows disease progression. The method is safer for the patient than thermal ablation methods and does not negatively affect the bile ducts. In some cases, the impossibility of surgically removing a tumor is determined during surgery, and simultaneous use of IRE Nano-Knife is permissible.
- Prostate cancer — surgical removal of tumors in this organ is often associated with the development of urinary disorders and erectile dysfunction. The use of IRE Nano-Knife for prostate cancer in Israel allows for the successful removal of tumors of any size without the risk of complications.
- Liver cancer — the use of this method is preferable because thermal ablation can damage nearby bile ducts and vessels.
- Kidney cancer — while standard ablation methods are indicated for the removal of malignant tumors no larger than 2 centimeters, IRE Nano-Knife allows for the removal of tumors larger than 3 centimeters with minimal trauma to the organ.
- Rectal cancer — tumor removal is performed without damaging the sphincter and the walls of the intestine.
Additionally, IRE Nano-Knife is used to treat malignant pathologies of the pelvic organs and thoracic cavity, as well as late-stage breast cancer.
Send your records — an Ichilov physician will reply within 1–2 days, free of charge.
What is IRE Nano-Knife and How is it Performed?
When high-voltage electric current is applied, micropores form in the membrane of the malignant cell, leading to loss of viability and cell death. The resulting breakdown products are absorbed into the lymphatic vessels and eliminated from the patient's body naturally.
The electric current is delivered through needle electrodes inserted into the affected area. The method of electrode insertion depends on the type of tumor. In the case of rectal tumors, the electrode is inserted through the anus; for prostate pathologies, it is inserted through the urethra; for malignant tumors located in the liver, pancreas, or kidney, it is done laparoscopically. Multiple electric impulses are applied to the area of malignant involvement for approximately 100 microseconds each. The electrodes move along the surface of the tumor, continuing the application until the entire tumor and a small area of healthy tissue are treated. The procedure is performed under general anesthesia, under the control of MRI, CT, or ultrasound, and lasts 1-2 hours.
During the procedure, cardiac activity is monitored using an ECG. Pulses are delivered between heartbeats, as these moments present the lowest risk of negative impact on heart rhythm.
After the procedure, it is recommended for the patient to stay in the clinic for 1-4 days.
Advantages of IRE Nano-Knife:
- Destructive effect on malignant cells, causing their death and natural elimination from the body.
- Non-surgical removal of more than five tumors in one session.
- Targeted impact on the tumor, without the risk of damaging healthy vessels and nerves.
- Absence of thermal impact that could damage surrounding tissues.
- Short duration of the procedure.
- Brief and easily manageable recovery period.
- Possibility of repeated procedures.
- Painless procedure with no postoperative scars.
IRE Nano-Knife in Israel: Prices
The cost of treatment depends on the type and size of the tumor, its location, the number of sessions, and the duration of the patient's stay in the clinic. The price of IRE Nano-Knife in Israel is on average 30-50% lower than in comparable Western European and American clinics.
- Liver Cancer
Advantages of Treatment in Israel
- Equipping clinics with state-of-the-art Nano-Knife systems.
- Procedures performed by highly qualified experienced specialists.
- Development of a detailed procedure plan.
- Constant visual monitoring.
- Reasonable prices.