Perinephritis is one of the well-known infectious-inflammatory diseases of the kidney, developing as a result of inflammation of the perirenal connective tissue. Treatment of perinephritis in Israel is carried out according to a scheme that depends on the form of the pathology and involves the use of the latest medications, as well as minimally invasive surgical procedures. Timely completion of the prescribed therapeutic course eliminates clinical symptoms in approximately 93-95% of cases, improves prognosis, and contributes to patient recovery. Treatment is provided by highly qualified doctors, many of whom are among the leading nephrologists in the world.
The chronic form of the disease, in which characteristic signs are absent or poorly expressed, often goes undetected for a long time. Modern high-precision diagnostic equipment in medical centers in Israel allows for the rapid identification of pathology, determination of structural and functional abnormalities of the kidneys and other internal organs, and assessment of the overall condition of the patient. Reviews from patients who have undergone treatment confirm its effectiveness and reasonable cost, comfortable conditions, attentiveness, and friendliness of the medical staff.
Treatment Methods for the Disease
Studies have shown that the prevalence of perinephritis is no more than 0.2-0.3%. Typically, the pathology develops in patients against the background of such kidney diseases as purulent pyelonephritis, urolithiasis, or as a complication of surgical intervention on the kidneys.
The causes of the disease are related to infection by pathogenic bacteria: most often various species of staphylococci, less frequently — streptococci, tuberculosis mycobacteria, pneumococci, and other pathogens. Purulent inflammation of the kidneys and purulent processes in nearby and distant internal organs contribute to the damage of the perirenal connective tissue. In some cases, the cause of the pathology remains unclear.
Depending on the cause of the disease, primary and secondary forms of perinephritis are distinguished. In the development of the primary pathological process, the infectious agent penetrates from a distant focus of inflammation hematogenously. As mentioned, approximately 80% of cases develop secondary perinephritis, which is a complication of an existing kidney disease.
The acute form of perinephritis is characterized by a sharp increase in temperature to 39-40℃, severe pain developing in the first days of the disease, and a serious general condition. It is typical for the affected side to have the leg flexed and drawn towards the abdomen. In the chronic form, the symptoms are blurred, the pain syndrome is less pronounced, and swelling and other symptoms are less evident.
As the disease progresses, the pus released enters the general bloodstream and spreads throughout the body, forming pathological foci in other organs. One of the most severe complications of perinephritis is the rupture of the abscess and the spillage of pus into various cavities. For instance, if the contents enter the abdominal cavity, the patient develops peritonitis, which requires urgent surgical treatment. Equally dangerous is the opening of the abscess into the pleural cavity, resulting in pyothorax — accumulation of pus in that area of the body.
In the case of diagnosing acute perinephritis, urgent hospitalization of the patient is indicated, while chronic forms of the pathology may allow for outpatient treatment. Various conservative or surgical methods are included in the therapy scheme depending on the nature of the inflammation and the form of the disease.
- Acute infiltrative perinephritis — medication treatment is indicated using the following drugs:
- antibiotics — cephalosporins of the 2nd-3rd generation, macrolides, semi-synthetic penicillins, fluoroquinolones, aminoglycosides;
- sulfanilamide drugs;
- immunomodulators;
- vitamin-mineral complexes.
- Acute purulent perinephritis — surgical sanitation of the pathological focus is indicated. Most patients undergo drainage via puncture, but surgical opening of the abscess (lumbar incision) is also possible. In severe cases, a nephrostomy is initially placed for the drainage of purulent contents, after which removal of the affected kidney (nephrectomy) is performed. After the surgical intervention, antibiotic therapy is prescribed.
- Chronic perinephritis — the treatment scheme includes both conservative and surgical techniques. In the absence of a formed purulent focus, medication treatment (antibiotics, glucocorticoids, resorptive agents) and various physiotherapeutic methods are prescribed. Surgical intervention is indicated based on the same principles as in the case of acute perinephritis.
In any form of perinephritis, the success of therapy is significantly enhanced by including physiotherapeutic methods such as UHF, diathermy, paraffin applications, mud therapy, and therapeutic massage in the program. In cases of septic complications and pronounced intoxication syndrome, the patient is prescribed hemodialysis, hemosorption, and plasmapheresis.
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Diagnostic Methods for the Disease
It is not always possible to promptly establish the correct diagnosis in cases of chronic or acute infiltrative perinephritis, as patients often present with vague symptoms. In diagnostic centers in Israel, the latest equipment allows for the examination of the patient in approximately three days, determining the cause of the pathology and developing a treatment program.
During the initial consultation with the leading nephrologist, which takes place immediately after the patient is admitted to the clinic, the doctor conducts a conversation with the patient, clarifies any recently suffered infectious diseases, and collects a detailed medical history. During a superficial examination, it is often possible to identify changes in the skin and muscle layer characteristic of this pathology, palpate the nodularity of the kidney surface, and detect the presence of an infiltrate. At the final stage of the appointment, the doctor compiles a list of necessary examinations.
On this day, the types of diagnostic procedures prescribed by the attending physician are performed:
- laboratory tests of urine and blood;
- ultrasound examination (US) of the kidneys and perirenal connective tissue;
- excretory urography (radiological examination of the kidneys);
- computed tomography (CT) of the kidneys;
- puncture of the perirenal connective tissue (obtaining tissue samples for subsequent determination of the presence of pathogenic agents and their sensitivity to antibiotics);
- kidney biopsy (performed for final confirmation of the diagnosis).
The results of the studies are submitted for review by a medical council, which includes the attending nephrologist and specialized specialists. After studying the obtained data, the doctors collectively establish the diagnosis and develop a treatment program.
What is the Cost of Treatment for the Disease
The cost of treatment is invariably of interest to medical tourists. It is noted that therapy in Israeli clinics is, on average, 30% cheaper than in Western European countries, allowing patients to save about 50% of the funds required for undergoing a therapeutic course in the USA.
Advantages of Treatment in Israel
- Effectiveness of the treatment provided.
- High level of qualification and global recognition of specialists.
- Modern material and technical base of clinics.
- Use of progressive therapy methods and the latest medications.
- Affordable prices.
Current achievements in medicine and pharmacology allow for successful management of the most severe rare diseases. By promptly contacting the chosen Israeli clinic and undergoing the prescribed treatment course, you can quickly overcome the illness and return to your usual life.