Treatment of eye and eyelid tumors at the Ichilov (Sourasky) clinic, Tel Aviv

Eye and eyelid tumors are a rare but highly specialized group of diseases that not only threaten life but also the preservation of vision and the patient's appearance. At the Ichilov (Sourasky) Medical Center in Tel Aviv, a dedicated team of ophthalmic oncologists, oculoplastic surgeons, radiation therapists, and medical oncologists collaborates closely with the ophthalmology department and the general oncology center to manage this pathology.

The hub covers the main types: eyelid tumors (basal cell and squamous cell carcinomas, sebaceous gland carcinoma, eyelid melanoma), uveal melanoma (of the eye's vascular layer), retinoblastoma in children, conjunctival and corneal tumors, orbital tumors (lymphomas, metastases, optic nerve gliomas), orbital pseudotumor, and inflammatory conditions requiring differential diagnosis.

Diagnosis at the clinic includes biomicroscopy, optical coherence tomography (OCT) of the anterior and posterior segments, A/B-scan ultrasound of the eye, MRI of the orbit with contrast (with fat-suppression), PET-CT when a systemic process is suspected, fine-needle biopsy under ultrasound guidance, and molecular testing (BAP1, GNAQ/GNA11 for uveal melanoma — critical for prognosis).

Surgical arsenal: Moos micro-surgery for eyelid tumors (preserving eyelid function and aesthetics), oculoplastic reconstruction of complex eyelid defects while maintaining blinking and tear drainage, resection of iridociliary tumors, organ-preserving brachytherapy with ¹⁰⁶Ru or ¹²⁵I plaques for uveal melanoma (preserving the eye and residual vision), proton therapy for complex localizations, enucleation and exenteration with endoprosthesis only for absolute indications. For retinoblastoma — intra-arterial chemotherapy, laser destruction, cryotherapy.

Below are articles on specific nosologies, diagnostic programs, and specialized ophthalmic oncology physicians at the Sourasky clinic.